• New set of normative data for Contact Heat Evoked Potentials (CHEPS) provided by a multicenter study

    30 May 2016

    The prestigious journal PAIN has recently published an extensive set of reference values for A-Delta mediated evoked potentials using Contact Heat stimulation, a technology patented by Medoc, using Pathway Model CHEPS platform.

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  • New study demonstrates long term relation between decline of peripheral nerve function and cumulative glycemic control

    31 March 2016

    This prospective observational study, conducted for 24 years on patients with diabetes type 1, demonstrated for the first time that peripheral and autonomic nerve dysfunction can be completely prevented by long-term near-normoglycemia, maintained from the diagnosis of type 1 diabetes.

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  • Y.Belenstein new Marketing Communications Manager

    22 March 2016

    Dear Partners,Mrs Yardena Belenstein - Medoc's new Marketing Communications Manager

    I am pleased to announce the appointment of Mrs. Yardena Belenstein to the position of Marketing Communications Manager, effective March 13th, 2016.

    Yardena brings extensive experience in marketing for medical devices companies. Over the past 3 years, Yardena has managed the marketing and branding for Alma Lasers (a global company of medical aesthetic platforms). Among her duties, Yardena managed exhibitions and events worldwide, created the B2B collateral, as well as B2C approached collateral.

    Prior to Alma Lasers, Yardena worked for Fortune 500 company Johnson & Johnson (medical devices) for 7 years.  In her role at J&J,  Yardena specialized in marketing for the Surgical franchise, with responsibility for management of websites (content, SEO and PPC), training and professional events, along with the implementation of global collateral to the local market.

    Please join me in wishing Yardena the very best in her new important position.


    Amir Haiman, General Manager

    Medoc Ltd, Advanced Medical Systems Division


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  • Prediction of Oxaliplatin-induced neuropathy using pretreatment QST

    3 March 2016

    Oxaliplatin is a chemotherapeutic agent widely used in cases of colorectal cancer. Together with its therapeutical effect there are various side effects oxaliplatine may cause, one of the most common of them is peripheral neuropathy.

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  • Determining heat and mechanical pain threshold

    10 February 2016

    The department of Anesthesia at Stanford University School of Medicine carries out its experiments using the following pain test paradigms: mechanical pain threshold tested with von Frey filaments and heat pain threshold evaluated using TSA II Neuro Sensory Analyzer.

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  • Examining penile sensitivity in neonatally circumcised and intact men using quantitative sensory testing

    1 February 2016

    The study is assessing penile sensitivity in circumcised and intact men by testing tactile and thermal thresholds at control site and few penile sites. The results demonstrate that circumcision procedure does not influence penile sensitivity and suggest that the foreskin is not the most sensitive part of the penis.

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  • Medoc and the community

    27 January 2016

    This week the Ruppin College hosted a unique skills day within the framework of “Young Israeli Entrepreneurs”. The children learned along the day about entrepreneurship, management, branding and defining roles, as well as raised funds for various purposes.

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  • A new promotion to the position of Operation & Service Manager of the Medical Systems Division

    24 January 2016

    Dear Partners,

    I am pleased to announce the appointment of Mr. David Gutmacher to the position of Operation & Service Manager of the Medical Systems Division ( QST Division), effective Jan. 1st, 2016.

    Since joining the company in Dec 2010, David has significantly strengthened the level and quality of our service commitment to Medoc customers. David has done so, while also playing an expanded role in operational areas beyond the service function.

    It is only natural that David receives this promotion, which is reflective of the confidence management has in his future and even wider contributions at Medoc.

    Please join me in wishing David the very best in his new and important position



    Amir Haiman, General Manager
    Medoc Ltd, Advanced Medical Systems Division

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  • CPM recommendation meeting at EFIC 2015

    4 November 2015


    Last September, at the 9th EFIC Pain Meeting, Medoc had sponsored a CPM Recommendation Meeting, organized and headed by Prof. Yarnitsky (Rambam Medical Center, Israel). This meeting is a follow up meeting to a previous CPM session, held during 2 years ago (2013) at the 8th EFIC meeting in Florence. Over 25 participants, KOLs in the field of CPM, attended this meeting trying to formulate additional recommendations for CPM method used for CPM studies. Some KOLs presented their way of doing CPM and the tools they use in their studies (cold/hot water bath, thermal probe, pressure algometer, blood pressure calf etc). The session gave the CPM specialist a great platform to address important questions such as the specifications of test and conditioning stimuli, distraction role, attempts to reach a standard CPM protocol, etc. Some of the participants shared the data they have collected, comparing different CPM methods, and their studies results. Medoc was pleased to sponsor this meeting and to get the CPM research community sharing their knowledge and take on this important subject.

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  • Methods to Measure Peripheral and Central Pain Sensitization Using Quantitative Sensory Testing: A Focus on Individuals with Low Back Pain

    4 November 2015

    This paper proposes a standardized method for performing various modalities of quantitative sensory testing (QST) in patients with low back pain. It concludes that such QST protocol can help to evaluate the mechanisms of low back pain – central and peripheral – and can be used for individualized treatment, based on the mechanism involved. Angela R. et al. Muscle Nerve.  2014.

    Quantitative sensory testing (QST) is a non-invasive method to evaluate the function of large and small nerve fibers and of peripheral and central sensory pathways. QST is used in many researches for various approaches, but standardization of the protocol is sometimes missing. This article’s purpose is to provide a standard protocol for using QST in patients with low back pain (LBP). The QST measures described in this paper are mechanical pain threshold and pain tolerance, mechanical temporal summation, dynamic mechanical allodynia; vibration detection threshold; thermal testings’ including warm and cold detection thresholds and heat and cold pain thresholds; conditioned pain modulation test (with thermal test and conditioning stimuli); thermal temporal summation; pressure pain threshold. The paper describes the protocol for each measurement, equipment used and analysis techniques. The paper emphasizes the importance of the measurement standardization, raises further steps that need to be taken to implement QST into the clinical practice and suggests that QST can be used for various approaches – detecting individual pain perception differences, dividing between peripheral and central mechanisms of pain, etc. – and also can serve to develop personalized treatment based on the individual pain mechanism and to evaluate the treatment effectiveness.
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